To study the neuronal mechanisms underlying the generation of distinct memories, it is necessary to perform experiments in which the sensory elements of the environment are under the precise control of the experimenter. To achieve this goal, we have developed a virtual-reality environment for rodents that we combine with imaging and electrophysiological methods to record the activity of individual neurons and populations of neurons while the animals are navigating in virtual reality. This system allows us to probe the neuronal mechanisms underlying spatial navigation and memory at the level of individual neurons and neuronal circuits. The goal of this project is to develop a modular recording and analysis pipeline that is both flexible and accessible to all experimental users, building on our existing software tools.