Expertise
Hub members Have many expertise, covering most of the fields in bioinformatics and biostatistics. You'll find below a non-exhaustive list of these expertise
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Searched keyword : RNA-seq
Related people (2)

Marie-Agnès DILLIES
I obtained an engineering degree in Biomedical engineering from Université de Technologie de Compiègne (UTC) in 1989, a master degree in Control of Complex Systems from UTC in 1990, a PhD in Control of Complex Systems from UTC in 1993, a University Degree in Human Genetics from The University of Rennes 1 in 2001 and a master degree in Functional Genomics from University Paris Diderot (Paris 7) in 2002. I worked as a statistician at the Transcriptome and Epigenome Platform from 2002 to 2017, where I was responsible for the statistical analyses of the data and had an important training activity (on the campus and outside). Since 2015 I have been co-head of the Bioinformatics and Biostatistics Hub within the Center of Bioinformatics, Biostatistics and Integrative Biology (C3BI). I am co-director of the Pasteur course Introduction to Data Analysis and co-organiser of the sincellTE summer school (a school dedicated to single cell transcriptome and epigenome data analysis). I am also co-managing the StatOmique group which gathers more than 60 statisticians from France.
KeywordsRNA-seqStatistical inferenceTranscriptomicsBiostatisticsApplication of mathematics in sciencesExploratory data analysisIllumina HiSeqStatistical experiment designSequencing
Organisms
Projects (3)
- Biomarqueurs d’identification précoce du sepsis aux urgences (BIPS)(Jean-Marc CAVAILLON - Cytokines and Inflammation) - Closed
- Study of the early pathogenesis during Lassa fever in cynomolgus monkeys and its correlation with the outcome(Sylvain BAIZE - Biology of Viral Emerging Infections) - In Progress
- Host microbiota modification by the pathogen Listeria monocytogenes(Javier PIZARRO-CERDA - Bacteria-Cell Interactions) - Closed

Violaine SAINT-ANDRÉ
After graduating from Paris VI University with a PhD in Genetics on the “Role of histone protein post-translational modifications in splicing regulation” that I performed in the Epigenetic Regulation unit at the Institut Pasteur, I carried out two post-doctoral experiences. I first worked for three years as a postdoctoral associate of the Whitehead Institute for Biomedical Research/MIT in Cambridge (USA). My main project consisted in the integration of genomic and epigenomic data in order to predict the transcription factors that are potentially at the core of the regulation of the cell-type specific gene expression programs. I then joined the Institut Curie where I deepened my experience in multi-omics data analyses and integration to identify non-coding RNAs involved in cancer progression. I have recently joined the HUB-C3BI of the Institut Pasteur where I am performing high-throughput data integration to better understand biological complexity and contribute to precision medicine development.
KeywordsATAC-seqChIP-seqEpigenomicsNon coding RNAPathway AnalysisRNA-seqSingle CellSystems BiologyTool DevelopmentTranscriptomicsData integrationGraph theory and analysisCell biology and developmental biology
Organisms
Human
Projects (1)
Related projects (55)
Transcriptome of Human sperm
Role of SUMO, a new epigenetic mark, in stress response
Mise a disposition d'un(e) bioinformaticien(ne) du hub pour les analyses bioinformatiques du transcriptome et de l epigenome
A long-term mission for an assigned CIH-embedded bioinformatician to provide bioinformatic support to the CIH community
ANALYSIS OF TRANSCRIPTIONNAL MODULATIONS INDUCED IN C57BL/6 BONE-MARROW DERIVED MACROPHAGES INFECTED BY LEISHMANIA AMAZONENSIS IN PRESENCE OR ABSENCE OF INFLAMMASOME-ACTIVATING CONDITIONS
individual-nucleotide resolution Cross-Linking and ImmunoPrecipitation (iCLIP) of Argonaute proteins in C. elegans
Development and use of statistical programs to analyze RNA-Seq data produced at the Transcriptome & Epigenome Platform
Nanotherapeutics for multidrug-resistant tuberculosis
Analysis of the transcriptome of malaria parasites
Identification of Tac4 mRNA targets
RNA analysis underlying phenotype of mouse model for autism
Characterization of the specific TCR repertoire preferentially expressed in spontaneously controlled HIV infection
Study of the early pathogenesis during Lassa fever in cynomolgus monkeys and its correlation with the outcome
- Thomas BIGOT
- Marie-Agnès DILLIES
- Rachel LEGENDRE + 2 operators
Discovery of non-annotated transcripts in RNAseq data from Aedes Aegypti
Characterization of an RNA binding protein of Listeria monocytogenes
Performing Gene Ontology Analysis on RNAseq data in Aedes aegypti
Transcriptional profile of Nod2+ neurons upon MDP signaling
identification of sRNA in Leptospira biflexa and influence of a putative Hfq on the transcriptome
Characterization of a Salmonella mutant carrying a single amino-acid substitution in the stress sigma factor RpoS
Genomic determinants for initiation and length of natural antisense transcripts in a compact eukaryotic genome and phylogenetic analysis of related Entamoeba species
Analysis of IFITM RNA levels in vraious cell types and tissues
Characterization of the role of Argonaute proteins in regulating germline gene expression at the transcriptional and the post-transcriptional levels.
Identification of Ago2-bound nuclear transcripts and genomic loci in adult zebrafish neural stem cells
characterization of RNA virus populations from untargeted NGS in natural infections samples
Transcriptomics of Anopheles – Plasmodium vivax interactions towards identification of malaria transmission blocking targets
Cellular plasticity during mammary gland development
Role of small non coding RNAs in the adaptive response to oxidative stress in pathogenic Leptospira
Genome-wide interactions between HP1g and RNA.
Determination of host response elicited by different Salmonella lifestyles
Gene expression and its regulation during and after inpatient detoxification of cocaine: a link to relapse?
Identifying subpopulation-specific signatures of tuberculosis persistence for enhanced diagnostics.
Early transcriptional signature of T-cell memory after dengue vaccination
Heterogeneity of the skeletal muscle microenvironment
Defining the differential contributions of CD4+ and CD8+ anti-CD19 CAR T cells to tumor outcome, immune recruitment and toxicity
Shigella targeting of human colonic Lamina Propria Mononuclear Cells
Identification of non-coding RNAs under the control of the PerR regulators
Modulation of cellular pathways involved in neuropathology of rabies infection
Transcriptional regulation of bacterial physiology during host-pathogen interaction
Left-right patterning of heart precursors
- Anne BITON
- Rachel LEGENDRE
- Emeline PERTHAME + 1 operator