Expertise
Hub members Have many expertise, covering most of the fields in bioinformatics and biostatistics. You'll find below a non-exhaustive list of these expertise
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Searched keyword : Statistical inference
Related people (8)

Marie-Agnès DILLIES
I obtained an engineering degree in Biomedical engineering from Université de Technologie de Compiègne (UTC) in 1989, a master degree in Control of Complex Systems from UTC in 1990, a PhD in Control of Complex Systems from UTC in 1993, a University Degree in Human Genetics from The University of Rennes 1 in 2001 and a master degree in Functional Genomics from University Paris Diderot (Paris 7) in 2002. I worked as a statistician at the Transcriptome and Epigenome Platform from 2002 to 2017, where I was responsible for the statistical analyses of the data and had an important training activity (on the campus and outside). Since 2015 I have been co-head of the Bioinformatics and Biostatistics Hub within the Center of Bioinformatics, Biostatistics and Integrative Biology (C3BI). I am co-director of the Pasteur course Introduction to Data Analysis and co-organiser of the sincellTE summer school (a school dedicated to single cell transcriptome and epigenome data analysis). I am also co-managing the StatOmique group which gathers more than 60 statisticians from France.
KeywordsRNA-seqStatistical inferenceTranscriptomicsBiostatisticsApplication of mathematics in sciencesExploratory data analysisIllumina HiSeqStatistical experiment designSequencing
Organisms
Projects (3)
- Biomarqueurs d’identification précoce du sepsis aux urgences (BIPS)(Jean-Marc CAVAILLON - Cytokines and Inflammation) - Awaiting Publication
- Study of the early pathogenesis during Lassa fever in cynomolgus monkeys and its correlation with the outcome(Sylvain BAIZE - Biology of Viral Emerging Infections) - In Progress
- Host microbiota modification by the pathogen Listeria monocytogenes(Javier PIZARRO-CERDA - Bacteria-Cell Interactions) - Closed

Vincent GUILLEMOT
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KeywordsData VisualizationMachine learningStatistical inferenceBiostatisticsApplication of mathematics in sciencesDimensional reductionMultidimensional data analysis
Organisms
Projects (20)
- Defining the effects of TNF-blockers and IL-17A-inhibitors on immune responses in spondyloarthritis patients, analysis of protein and gene expression signatures(Lars ROGGE - Immunoregulation) - In Progress
- Coaching in R(Elisabetta BIANCHI - Immunoregulation) - In Progress
- Collaboration between CETEA, C2RA and Hub for optimization of experimental designs (3R)(Myriam MATTEI - Center for Animal Resources and Research) - In Progress

François LAURENT
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KeywordsData managementMachine learningStatistical inferenceScientific computingExploratory data analysisSofware development and engineeringParallel computingNeuroimaging and computational neuroscienceGrid and cloud computing
Organisms
Projects (0)

Gael MILLOT
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KeywordsImage analysisStatistical inferenceBiostatisticsGeneticsSequencingDiagnostic tools
Organisms
Projects (18)
- Analysis of genes transcription profiles in E.coli after expression of the T4 phage protein Ndd(Foutel-Rodier THÉO - Spatial Regulation of Genomes) - In Progress
- Single-cell characterization of autoreactive IgG-secreting cells in Immune thrombocytopenia(Pablo CANALES HERRERIAS - Antibodies in Therapy and Pathology) - In Progress
- Phages - bacteria interactions network of the healthy human gut(Martial MARBOUTY - Spatial Regulation of Genomes) - Awaiting Publication

Emeline PERTHAME
Since February 2017 Research engineer, Hub of Bioinformatics and Biostatistics of the C3BI, Institut Pasteur 2015-2017 Post doctoral position, team MISTIS, INRIA Grenoble Topic: Robust clustering and robust non linear regression in high dimension. Collaboration with Florence Forbes (INRIA). 2012-2015 PhD thesis in Statistics, Applied Mathematics Department of Agrocampus-Ouest, IRMAR UMR 6625 CNRS, Rennes Topic: Stability of variable selection in regression and classification issues for correlated data in high dimension. Supervisor: David Causeur (Agrocampus-Ouest, IRMAR). Education 2015 PhD thesis in Statistics, Applied Mathematics Department of Agrocampus-Ouest, IRMAR UMR 6625 CNRS, Rennes 2012 ISUP degree (Institut de Statistique de l’UPMC), Université Pierre et Marie Curie, Paris 2012 Master 2 of Statistics, Université Pierre et Marie Curie, Paris
KeywordsClusteringModelingStatistical inferenceTranscriptomicsBiostatisticsExploratory data analysisDimensional reductionStatistical experiment designMultidimensional data analysis
Organisms
Projects (22)
- Asymmetric heart morphogenesis(BERNHEIM SÉGOLÈNE - Heart Morphogenesis) - In Progress
- Modulation of Flu transmission in Niger , according to climate variations over the past ten years(Ronan JAMBOU - Other) - In Progress
- Left-right patterning of heart precursors(Tobias BØNNELYKKE - Heart Morphogenesis) - In Progress

Hugo VARET
Hugo Varet is a biostatistician engineer from the Ensai (Ecole Nationale de la Statistique et de l’Analyse de l’Information) and has been recruited in 2013 by the Transcriptome & Epigenome Platform of the Biomics Pole. Late 2014 he obtained a permanent position at the Bioinformatics & Biostatistics Hub and has been detached to the platform to continue the statistical analyses of RNA-Seq data and develop R pipelines and Shiny applications that help in this task. One of them is named SARTools and is available on GitHub: https://github.com/PF2-pasteur-fr/SARTools. In December 2019 he left the Biomics Platform and joined the Bioinformatics & Biostatistics Hub as a core-member.
KeywordsModelingSequence analysisStatistical inferenceTranscriptomicsBiostatisticsScientific computingApplication of mathematics in sciencesExploratory data analysisHigh Throughput ScreeningClinical research
Organisms
Projects (26)
- Transcriptional analysis of injured skeletal muscle(Eleonora ROSSI - Stroma, Inflammation and Tissue Repair) - Closed
- Correlative analysis between lipid droplets number and volume in hepatocytes infected by hepatitis C virus variants(Emeline SIMON - Molecular Genetics of RNA Viruses) - Closed
- Analysis of the transcriptome during lyssavirus infection in torpid bat: an in vitro model. Act 1(Laurent DACHEUX - Lyssavirus Dynamics and Host Adaptation) - In Progress

Stevenn VOLANT
After a diploma of statistician engineer from the Ensai (Ecole Nationale de la Statistique et de l’Analyse de l’Information) and a Ph.D in applied mathematics in the Statistics & Genome lab (AgroParisTech), I worked as a developer for the XLSTAT software. I have implemented some statistical methods such as mixture models, log-linear regression, mood test, bayesian hierarchical modeling CBC/HB, … Then I worked as a head teacher in statistics for one year. I was recruited in the Bioinformatic and biostatistic hub of the C3BI (Center of Bioinformatics, Biostatistics and Integrative Biology) in 2014, I am in charge of the statistical analysis and the development of R/R shiny pipelines.
KeywordsMachine learningStatistical inferenceTargeted metagenomicsBiostatisticsApplication of mathematics in sciencesStatistical experiment design
Organisms
Projects (31)
- Validation of interactions between SARS-CoV-2 proteins and cellular proteins(Guillaume DUGIED - Molecular Genetics of RNA Viruses) - Pending
- Transcriptional profiling of the innate immune response of human fibroblasts of the LabEx Milieu interieur collection: interindividual variability and response to infection(Brigitte DAVID-WATINE - Photonic BioImaging (UTechS PBI)) - Pending
- Induction of highly efficient HIV-specific CD8+ T cell responses(ASIER SAEZ-CIRION - HIV, Inflammation and Persistence) - In Progress