Project #11315
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#11315 : Next Generation Surveillance of Salmonella and Shigella infections
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Organisms :
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Name of Applicant : Francois-Xavier Weill
Date of application : 29-03-2018
Unit : Enteric Bacterial Pathogens
Location : BioTop -3rd
Phone : 8345
@ Mail :

Project context and summary :

Whole genome sequencing is revolutionizing the surveillance of foodborne and waterborne bacterial pathogens. The speed with which public health laboratories obtain information after the onset of symptoms and the regular sharing of this information between public health laboratories and epidemiologists are critical for the successful use of information to detect outbreaks early and to identify their source. For this purpose, this project aims at providing the most relevant bacterial genomic information in a timely-manner by integrating different validated in silico tools (core genome MLST, CRISPR, O and H molecular serotype, ....) into a single automated analysis pipeline.

Related team publications :
Tran Dien et al. Early transmissible ampicillin resistance in zoonotic Salmonella Typhimurium: a retrospective, whole-genome sequencing study. Lancet Infect Dis. 2018 Feb;18(2):207-214.
Weill et al. Genomic history of the seventh pandemic of cholera in Africa. Science. 2017 Nov 10;358(6364):785-789.
Njamkepo et al. Global phylogeography and evolutionary history of Shigella dysenteriae type 1. Nat Microbiol. 2016 Mar 21;1:16027.
Service Delivery
Status : Declined

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