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Project #12619
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#12619 : Asymptomatic pathogen carriage in stunted and non-stunted children living in Antananarivo, Madagascar
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Name of Applicant : Pascale Vonaesch
Date of application : 23-11-2018
Unit : Molecular Microbial Pathogenesis
Location : Duclaux, Bertrand, 1er ├ętage, salle 01B
Phone : poste 9576
@ Mail : pascale.vonasch@pasteur.fr
@ PI-Mail : philippe.sansonetti@pasteur.fr

Project context and summary :

This project is integrated in the analysis of the gut ecosystem of children implicated in the AFRIBIOTA project, a translational project performed within a consortium of researchers and medical doctors from the Central African Republic, Madagascar, France and Canada (see https://research.pasteur.fr/fr/program_project/the-afribiota-project/). AFRIBIOTA aims at understanding the risk factors and pathophysiological changes underlying chronic child malnutrition as manifested through delayed growth. Within the project submitted, we aim at assessing a possible link between asymptomatic pathogen carriage, gut inflammation and stunted growth of children included in the study site in Antananarivo, Madagascar.


Related team publications :
Vonaesch et al., PNAS 2018: Stunted childhood growth is associated with decompartmentalization of the gastrointestinal tract and overgrowth of oropharyngeal taxa.
Vonaesch et al., BMC Paediatrics 2018: Identifying the etiology and pathophysiology underlying stunting and environmental enteropathy: study protocol of the AFRIBIOTA project.
Vonaesch et al., FEMS Microbiology Reviews 2018: Pathogens, microbiome and the host: emergence of the ecological Koch’s postulates.
Service Delivery
Project Manager : vincent.guillemot@pasteur.fr
Project Type : Short
Status : In Progress


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