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Project #13412
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#13412 : Analysis of the clinical manifestations of Lyme borreliosis in France from 2003 to 2011
Topics :
Organisms :
Group :
Name of Applicant : Valerie Choumet
Date of application : 17-07-2019
Unit : Environment and Infectious Risks
Location : Darré 1rst floor room 10A
Phone : 0145698630
@ Mail : vchoumet@pasteur.fr
@ PI-Mail : jean-claude.manuguerra@pasteur.fr

Project context and summary :

Lyme borreliosis (LB) is an important tick-borne disease which can cause a broad range of symptoms mainly affecting the skin, the nervous system and the joints. It is caused by bacteria of the Borrelia burgdorferi sensu lato (s.l.) complex. In Europe, at least five genospecies are known to be pathogenic, namely Borrelia afzelii, Borrelia garinii, B. burgdorferi sensu stricto, Borrelia spielmanii and Borrelia bavariensis. In order to assess the health burden, data on the incidence of all the different clinical manifestations are required. The National Reference Centre for Borrelia collected epdiemiological, clinical and biological data from general practioners and hospitals of patients bitten by Ixodes ticks from 2003 to 2011. This large amount of data needs statistical analyses both univariate and univariate in order to obtain a global and precise vision of all the elements allowing us to understand this disease, both in the complexity of its symptoms and its management but also in the context of its prevention.


Related team publications :
Retrospective Study of Lyme Borreliosis Serologies in France: Evolution between 2007 and 2011. Loïc Chartier, Sabine Trombert-Paolantoni, Sylvie Gonzalo, Elisabeth Ferquel, Valérie Choumet. JSM Tropical Medicine and Research, JSciMed Central, 2017, 2 (1), pp.1013.
Infection Kinetics and Tropism of Borrelia burgdorferi sensu lato in Mouse After Natural (via Ticks) or Artificial (Needle) Infection Depends on the Bacterial Strain. Sertour N, Cotté V, Garnier M, Malandrin L, Ferquel E, Choumet V. Front Microbiol. 2018 Jul 31;9:1722.
Infection of Ixodes ricinus by Borrelia burgdorferi sensu lato in peri-urban forests of France. Marchant A, Le Coupanec A, Joly C, Perthame E, Sertour N, Garnier M, Godard V, Ferquel E, Choumet V. PLoS One. 2017 Aug 28;12(8):e0183543
Service Delivery
Project Manager : emeline.perthame@pasteur.fr
Project Type : Short
Status : In Progress


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