Project #14967
Step by step one goes very far

Logged as guest

Go Back to Project List
#14967 : Transcriptional regulation of bacterial physiology during host-pathogen interaction
Topics :
Organisms :
Group :
Name of Applicant : Arnaud FIRON
Date of application : 22-01-2020
Unit : Biology of Gram-Positive Pathogens
Location : 03-01-02
Phone : +33 1 40 61 36 76
@ Mail :
@ PI-Mail :

Project context and summary :

The aim of this RNA-seq project is to characterize three transcriptional regulators of Streptococcus agalactiae, the main etiological agent of bacterial meningitis in neonate, and one transcriptional factor of Enterococcus faecalis, a second Gram-positive opportunistic pathogen.

Related team publications :
Devaux L, et al. Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus. PLoS Genet 14, e1007342 (2018)
Lentini G, et al. The plasminogen binding protein PbsP is required for brain invasion by hypervirulent CC17 Group B streptococci. Scientific reports 8, 14322 (2018)
Firon A, et al. The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus. PLoS Pathog 9, e1003179 (2013)
Service Delivery
Project Manager :
Project Type : Medium
Status : Closed
Publication : 10.1371/journal.pgen.1009761
Global Satisfaction for this application : Excellent (5/5)

Go Back to Project List

Sorry. You must be logged in to view this form.