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Project #15355
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#15355 : Biology of noncoding regulatory elements in Anopheles
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Name of Applicant : Kenneth VERNICK
Date of application : 07-06-2020
Unit : Genetics and Genomics of Insect Vectors
Location : Sergent - 3rd floor
Phone : 3642
@ Mail : kvernick@pasteur.fr

Project context and summary :

Enhancers are cis-regulatory elements that control developmental and spatial gene expression in eukaryotes. Enhancers have been little studied in mosquitoes, including the Anopheles vectors of malaria.


Related team publications :
Nardini, L., Holm, I., Pain, A., Bischoff, E., Gohl, D.M., Zongo, S., Guelbeogo, W.M., Sagnon, N., Vernick, K.D., and Riehle, M.M. (2019). Influence of genetic polymorphism on transcriptional enhancer activity in the malaria vector Anopheles coluzzii. Sci Rep 9, 15275.
Riehle, M.M., Bukhari, T., Gneme, A., Guelbeogo, W.M., Coulibaly, B., Fofana, A., Pain, A., Bischoff, E., Renaud, F., Beavogui, A.H., et al. (2017). The Anopheles gambiae 2La chromosome inversion is associated with susceptibility to Plasmodium falciparum in Africa. Elife 6.
Mitri, C., Bischoff, E., Takashima, E., Williams, M., Eiglmeier, K., Pain, A., Guelbeogo, W.M., Gneme, A., Brito-Fravallo, E., Holm, I., et al. (2015). An Evolution-Based Screen for Genetic Differentiation between Anopheles Sister Taxa Enriches for Detection of Functional Immune Factors. PLoS Pathog 11, e1005306.
Service Delivery
Project Manager : adrien.pain@pasteur.fr
Project Type : Medium
Status : Pending


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