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Project #16693
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#16693 : Mosquito vector competence for different RVFV variants
Topics : Organisms :
Group : Name of Applicant : Pei-Shi YEN Date of application : 27-01-2021 Unit : Arboviruses and Insect Vectors Location : Nicolle-RDV-03 Phone : 0144389127@ Mail : pei-shi.yen@pasteur.fr@ PI-Mail : anna-bella.failloux@pasteur.fr
Project context and summary :
Historically circulating in Africa, Rift Valley fever virus (RVFV) was firstly identified in Kenya in 1930, and responsible for dozens of outbreaks in Africa in the past decades. As an arbovirus, RVFV is mainly transmitted by mosquito vector, and needs to be altered between mammalian host and mosquito vector for maintaining the genome stability. In this project, we are analysing the mosquito vector competence for several RVFV variants obtained from different host cells, to better interpret the risk factors of transmission.
Related team publications :Sara Moutailler, Benjamin Roche, Jean-Michel Thiberge, Valérie Caro, François Rougeon, and Anna-Bella Failloux Host Alternation Is Necessary to Maintain the Genome Stability of Rift Valley Fever Virus. PLoS Negl Trop Dis. 2011 May; 5(5): e1156.
Sara Moutailler, Ghazi Krida, Francis Schaffner, Marie Vazeille, Anna-Bella Failloux Potential vectors of Rift Valley fever virus in the Mediterranean region. Vector Borne Zoonotic Dis . 2008 Dec;8(6):749-53. doi: 10.1089/vbz.2008.0009.
Service Delivery
Project Manager : pierre.lechat@pasteur.frStatus : Pending