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Project #16959
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#16959 : Imprinting by immune cross regulation modulate airway allergic inflammation
Topics : Organisms :
Group : Name of Applicant : Jaechan RYU Date of application : 20-05-2021 Unit : Microenvironment and Immunity Location : Mechnikoff-RDC-33 Phone : 3732@ Mail : jaechan.ryu@pasteur.fr@ PI-Mail : gerard.eberl@pasteur.fr
Project context and summary :
There are papain treated and papain+CPG treated group. From mouse lung tissue, I'd like to find out the target cell and their key molecule through scRNAseq and receptor-ligand analysis. When I get the target cell, I want to do ATACseq (or scATACseq) of target cell to see if memory of previous exposure to inflammatory stimuli represented by chromatin accessibility and which has something to do with 2nd exposure of same allergen.
Related team publications : Service Delivery
Project Manager : olivier.mirabeau@pasteur.frProject Type : MediumStatus : Pending