Project #17277
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#17277 : Analysis of the viral diversity of coronaviruses in field samples.
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Name of Applicant : Berthet Nicolas
Date of application : 20-07-2021
Unit : Other
Location : Shanghai
Phone : +33685056674
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Project context and summary :

Advances in high-throughput sequencing may allow more rapid characterisation of viral diversity in samples. However, although there are many tools to perform taxonimuqye assignment of the reads obtained, there is no automated pipeline to obtain the different sequences by species and genus, and when the depth is sufficient to apply correction algorithms. In the end, obtaining these sequences will allow us to better understand the diversity and prevalence of each of the species highlighted in our samples.

Related team publications :
Berthet N, Descorps-Declère S, Besombes C, Curaudeau M, Nkili Meyong AA, Selekon B, Labouba I, Gonofio EC, Ouilibona RS, Simo Tchetgna HD, Feher M, Fontanet A, Kazanji M, Manuguerra JC, Hassanin A, Gessain A, Nakoune E. Genomic history of human monkey pox infections in the Central African Republic between 2001 and 2018. Sci Rep. 2021 Jun 22;11(1):13085.
Simo Tchetgna H, Descorps-Declère S, Selekon B, Kwasiborski A, Vandenbogaert M, Manuguerra JC, Gessain A, Caro V, Nakouné E, Berthet N. Molecular characterization of a new highly divergent Mobala related arenavirus isolated from Praomys sp. rodents. Sci Rep. 2021 May 13;11(1):10188.
Maganga Gaël*, Kapetshi J*, Berthet N*, Kebela Ilunga B, Kabange F, Mbala Kingebeni P, Mondonge V, Muyembe JJ, Bertherat E, Briand S, Cabore J, Epelboin A, Formenty P, Kobinger G, González-Angulo L, Labouba I, Manuguerra JC, Okwo-Bele JM, Dye C, Leroy EM. Ebola virus disease in the Democratic Republic of Congo. N Engl J Med. 2014 Nov 27;371(22):2083-91.Analysis of the viral diversity of coronaviruses in field samples.
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Status : In Progress

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