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Project #17884
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#17884 : Identification of factors influencing the activity of bacteriophage within the gut of mammals
Topics :
Organisms :
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Name of Applicant : Devon Conti
Date of application : 27-12-2021
Unit : Other
Location : Fernbach-3rd floor-3026A
Phone : 0033769921085
@ Mail : devon.conti@pasteur.fr
@ PI-Mail : laurent.debarbieux@pasteur.fr

Project context and summary :

We aim to characterise the transcriptome of OMM12 mice under different experimental conditions


Related team publications :
Chaffringeon L, Lamy-Besnier Q, Debarbieux L, De Sordi L. The intestinal virome: lessons from animal models. Curr Opin Virol. 2021 Dec;51:141-148. doi: 10.1016/j.coviro.2021.09.016. Epub 2021 Oct 23. PMID: 34700287.
Lamy-Besnier Q, Chaffringeon L, Lourenço M, Payne RB, Trinh JT, Schwartz JA, Sulakvelidze A, Debarbieux L. Prophylactic Administration of a Bacteriophage Cocktail Is Safe and Effective in Reducing Salmonella enterica Serovar Typhimurium Burden in Vivo. Microbiol Spectr. 2021 Sep 3;9(1):e0049721. doi: 10.1128/Spectrum.00497-21. Epub 2021 Aug 25. PMID: 34431719; PMCID: PMC8552648.
Lourenço M, Chaffringeon L, Lamy-Besnier Q, Pédron T, Campagne P, Eberl C, Bérard M, Stecher B, Debarbieux L, De Sordi L. The Spatial Heterogeneity of the Gut Limits Predation and Fosters Coexistence of Bacteria and Bacteriophages. Cell Host Microbe. 2020 Sep 9;28(3):390-401.e5. doi: 10.1016/j.chom.2020.06.002. Epub 2020 Jul 1. PMID: 32615090.
Service Delivery
Project Manager : rachel.legendre@pasteur.fr
Project Type : Medium
Status : In Progress


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