Project

Project #2409
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Topics :

Data Visualization Differential analysis Genomics Metabolomics Proteomics Transcriptomics

Organisms :

Parasite Leishmania donovani

Group :

TEG

Name of Applicant : Pascale Pescher
Date of application : 30-09-2015
Unit : Molecular Parasitology and Signaling
Location : Calmette – 02 – 06c
Phone : 01 40 61 35 32
@ Mail : pascale.pescher@pasteur.fr
@ PI-Mail : gerald.spaeth@pasteur.fr

Project context and summary :

The aim of the project is to create a viewer that will help visualisation and correlation between genomic, transcriptomic, proteomic and metabolomic data generated by the comparison of amastigote and promastigote stages of the Leishmania donovani parasite.

Related team publications :

Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation. Pescher P, Blisnick T, Bastin P, Späth GF. Cell Microbiol. 2011 Jul;13(7):978-91.

Phosphoproteomic analysis of wild-type and antimony-resistant Leishmania braziliensis lines by 2D-DIGE technology. Moreira Dde S, Pescher P, Laurent C, Lenormand P, Späth GF, Murta SM. Proteomics. 2015 Sep;15(17):2999-3019.

Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses. Dacher M, Morales MA, Pescher P, Leclercq O, Rachidi N, Prina E, Cayla M, Descoteaux A, Späth GF. Mol Microbiol. 2014 Jul;93(1):146-66.

Project Manager : christophe.becavin@pasteur.fr
Project Type : Long
Status : In Progress

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