Project
Project #2409
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#2409 : Systems wide analysis of amastigote and promastigote stages of Leishmania donovani
Topics : Organisms :
Group : Name of Applicant : Pascale Pescher Date of application : 30-09-2015 Unit : Molecular Parasitology and Signaling Location : Calmette - 02 - 06c Phone : 01 40 61 35 32@ Mail : pascale.pescher@pasteur.fr@ PI-Mail : gerald.spaeth@pasteur.fr
Project context and summary :
The aim of the project is to create a viewer that will help visualisation and correlation between genomic, transcriptomic, proteomic and metabolomic data generated by the comparison of amastigote and promastigote stages of the Leishmania donovani parasite.
Related team publications :Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation. Pescher P, Blisnick T, Bastin P, Späth GF. Cell Microbiol. 2011 Jul;13(7):978-91.
Phosphoproteomic analysis of wild-type and antimony-resistant Leishmania braziliensis lines by 2D-DIGE technology. Moreira Dde S, Pescher P, Laurent C, Lenormand P, Späth GF, Murta SM. Proteomics. 2015 Sep;15(17):2999-3019.
Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses. Dacher M, Morales MA, Pescher P, Leclercq O, Rachidi N, Prina E, Cayla M, Descoteaux A, Späth GF. Mol Microbiol. 2014 Jul;93(1):146-66.
Service Delivery
Project Manager : christophe.becavin@pasteur.frProject Type : LongStatus : Closed