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Project #2497
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#2497 : Methods to identify and characterize orthologs of genes encoding small proteins
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Group : Name of Applicant : Françoise Norel Date of application : 03-03-2015 Unit : Macromolecular Systems and Signaling Location : Monod (66) – 5eme etage Phone : 0140613122@ Mail : francoise.norel@pasteur.fr
Project context and summary :
We wish to investigate the extent of conservation and prevalence of small orfs of unknown function expressed in stationary phase of growth in Salmonella
Related team publications :Repressor activity of the RpoS/σS-dependent RNA polymerase requires DNA binding. Lévi-Meyrueis C, Monteil V, Sismeiro O, Dillies MA, Kolb A, Monot M, Dupuy B, Duarte SS, Jagla B, Coppée JY, Beraud M, Norel F. Nucleic Acids Res. 2015 Feb 18;43(3):1456-68
Expanding the RpoS/σS-network by RNA sequencing and identification of σS-controlled small RNAs in Salmonella. Lévi-Meyrueis C, Monteil V, Sismeiro O, Dillies MA, Monot M, Jagla B, Coppée JY, Dupuy B, Norel F. PLoS One. 2014 May 8;9(5):e96918.
Structural and functional features of Crl proteins and identification of conserved surface residues required for interaction with the RpoS/σS subunit of RNA polymerase. Cavaliere P, Levi-Acobas F, Mayer C, Saul FA, England P, Weber P, Raynal B, Monteil V, Bellalou J, Haouz A, Norel F. Biochem J. 2014 Oct 15;463(2):215-24.
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Project Manager : julien.guglielmini@pasteur.frProject Type : LongStatus : ClosedPublication : 10.1038/s41598-017-02362-3Global Satisfaction for this application : Pretty Good (4/5)