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Project #2598
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#2598 : Updating the Topo IB gene tree
Topics :
Organisms :
Group :
Name of Applicant : Patrick Forterre
Date of application : 09-04-2015
Unit : Molecular Biology of Gene in Extremophiles
Location : Fernbach (68) – 3rd – 38
Phone : 01 45 68 87 91
@ Mail : dmornico@pasteur.fr

Project context and summary :

DNA topoisomerase IB (Topo IB) enzymes are ubiquitous in eukaryotes, where they represent the major DNA topoisomerase I activity. However, Topo IB sequences are also found in other phyla, such as archaea and bacteria, as well as viruses. Given the large amount of sequenced data available in public databases, this project aims to infer a robust Topo IB gene tree based on a representative set of homologous sequences gathered from a large taxonomic sample.


Related team publications :
Brochier-Armanet et al. Biology Direct 2008, 3:54
Forterre et al. Biochimie 2007, 89:427-446
Service Delivery
Project Manager : alexis.criscuolo@pasteur.fr
Project Type : Medium
Status : Closed
Publication : 10.1093/nar/gkw097


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