Project

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Name of Applicant : Patrick Forterre
Date of application : 09-04-2015
Unit : Molecular Biology of Gene in Extremophiles
Location : Fernbach (68) – 3rd – 38
Phone : 01 45 68 87 91
@ Mail : dmornico@pasteur.fr

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Project context and summary :

DNA topoisomerase IB (Topo IB) enzymes are ubiquitous in eukaryotes, where they represent the major DNA topoisomerase I activity. However, Topo IB sequences are also found in other phyla, such as archaea and bacteria, as well as viruses. Given the large amount of sequenced data available in public databases, this project aims to infer a robust Topo IB gene tree based on a representative set of homologous sequences gathered from a large taxonomic sample.

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