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Project #2892
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#2892 : The Physiological Consequences of Altering Bacterial Cell Wall Synthesis
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Name of Applicant : Joel Berry
Date of application : 04-12-2015
Unit : Biology and Genetics of Bacterial Cell Wall
Location : Duclaux aille Bertrand RDC-bas
Phone : 682641305
@ Mail : jberry@pasteur.fr
@ PI-Mail : bonecai@pasteur.fr

Project context and summary :

Currently there is increased focus for developing novel antibacterial strategies. The demand is driven by the rise in antibiotic resistance bacteria and many Gram-negative bacteria are on the list of increasingly drug resistant agents. A major target of successful antibiotics is the bacterial cell wall. The target of these drugs is often defined but what is much less understood is the off-target impact of these very important antibiotics. We designed and executed a mutli-omics strategy centered on the Gram-negative pathogen H. pylori. Our goal is to identify potential ‘therapeutically susceptible’ pathways associated with the physiological response to cell wall stress.


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Service Delivery
Project Manager : christophe.becavin@pasteur.fr
Project Type : Medium
Status : Closed
Global Satisfaction for this application : Pretty Good (4/5)


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