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Project #3442
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#3442 : Reconstruction of archaeal genomes from environmental metagenomic data
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Name of Applicant : simonetta gribaldo
Date of application : 02-02-2016
Unit : Molecular Biology of Gene in Extremophiles
Location : Fernbach
Phone : 9455
@ Mail : simonetta.gribaldo@pasteur.fr

Project context and summary :

A large fraction of diversity of the Archaea is still poorly explored. We are targeting environmental samples to extract genomic data of archaeal lineages of specific interest from an evolutionary point of view. We will probe available sequence data from public environmental metagenomics databases to identify specific lineages. In parallel, we will produce our own data from selected environmental samples containing these lineages. These data will allow filling up poorly explored branches of the tree of Archaea and bring important information on the metabolic diversity and adaptation to various environmental conditions, including the human microbiome.  


Related team publications :
Borrel G, O’Toole P, Peyret P, Brugère JF, and Gribaldo S (2013) Phylogenomic data support a seventh order of methylotrophic methanogens and provide insights into the evolution of methanogenesis. Genome Biol Evol. 5(10):1769-80
Raymann K, Brochier-Armanet C, Gribaldo S (2015) The two-domain tree of life is linked to a new root for the Archaea. Proc Natl Acad Sci U S A 112(21):6670-5.
Brochier-Armanet C, Forterre P, Gribaldo S (2011) Phylogeny and evolution of the Archaea: one hundred genomes later. Curr Opin Microbiol. 14(3):274-81. REVIEW
Service Delivery
Project Manager : quentin.letourneur@pasteur.fr
Project Type : Long
Status : Awaiting Publication


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