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Project #7074
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#7074 : Gene Ontology and sequence analysis of proteomics data on mycolactone effects on dendritic cells.
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Group : Name of Applicant : Jean-David Morel Date of application : 13-09-2016 Unit : Immunobiology of Infection Location : Metchnikoff-5th floor-5041 Phone : 0140613892@ Mail : jean-david.morel@pasteur.fr@ PI-Mail : caroline.demangel@pasteur.fr
Project context and summary :
Mycolactone, the lipid toxin produced by Mycobacterium ulcerans, has recently been shown to target the Sec61 transolcon, blocking protein translocation accross the ER membrane. As Sec61 has also been proposed as a critical mediator in cross-presentation in dendritic cells, this analysis aims to analyse mycolactone effects on the proteome of dendritic cells.
Related team publications : Service Delivery
Project Manager : natalia.pietrosemoli@pasteur.frProject Type : ShortStatus : ClosedPublication : 10.1073/pnas.1705242114Global Satisfaction for this application : Pretty Good (4/5)