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Project #7331
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#7331 : Analysis of DNA methylation in the presence and absence of antibiotics in wt and mutant V. cholerae.
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Name of Applicant : zeynep Baharoglu
Date of application : 08-11-2016
Unit : Bacterial Genome Plasticity
Location : 27-02-03
Phone : 9483
@ Mail : baharogl@pasteur.fr
@ PI-Mail : mazel@pasteur.fr

Project context and summary :

Thanks to RNA-Seq experiments we identified  a new orphan DNA methylase (not associated with a restriction enzyme) that is highly upregulated in the presence of low concentrations of aminoglycosides in V. cholerae. The results allow us to consider a differential DNA methylation profile depending on the environment (with or without antibiotics), which can possibly correspond to a novel epigenetic control of the response.


Related team publications :
PMID: 24319148
PMID: 23613664
PMID: 21300836
Service Delivery
Project Manager : claudia.chica@pasteur.fr
Project Type : Medium
Status : Closed
Global Satisfaction for this application : Excellent (5/5)


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