Project #8202
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#8202 : Transcriptomic analysis of blood cells from ebola infected patients
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Name of Applicant : Stéphanie REYNARD
Date of application : 14-04-2017
Unit : Biology of Viral Emerging Infections
Location : Lyon Tour Cervi
Phone : 04 37 28 24 52
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Project context and summary :

Blood cells were collected in the field from patients admited in the Ebola treatment center of Macenta (Guinea). After red cells lysis, blood cells were frozen and RNA was extracted after the shipment of samples in France. Despite poor RNA quality, Affimetrix chips have been performed and transcriptomic data are available. The aim of this study is to compare the transcriptomic data from patients who survived and those who died and also to perform a kinetic analysis of the infection in the two groups of patients.  Samples from febrile patients who were not infected with Ebola virus have been used as negative controls.

Related team publications :
JCI Insight. 2017 Mar 23;2(6):e88864. doi: 10.1172/jci.insight.88864. Clinical, virological, and biological parameters associated with outcomes of Ebola virus infection in Macenta, Guinea.
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Project Type : Short
Status : Closed
Publication : doi: 10.3390/v11030287
Global Satisfaction for this application : Excellent (5/5)

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