Genomic enzymology web tools for functional assignment: Generating and analyzing Sequence Similarity Networks (SSNs) and Genome Neighborhood Networks (GNNs) with the EFI suite

EVENT : C3BI Seminars Main speaker : Rémy Zallot, from University of Illinois Date : 20-06-2019 at 02:00 pm Location : Duclaux room down groundfloor – DUCLAUX (01), Institut Pasteur, Paris Protein databases contain an exponentially growing number of sequences as a result of the decrease of cost and difficulty of genome sequencing. The rate … Continue reading “Genomic enzymology web tools for functional assignment: Generating and analyzing Sequence Similarity Networks (SSNs) and Genome Neighborhood Networks (GNNs) with the EFI suite”

New computational tools for the analysis of microbiome dynamics

EVENT : C3BI Seminars Main speaker : Eran Halperin, from UCLA (Computer Science Department & Departments of Human Genetics, Biomathematics & Department of Anesthesiology) Date : 25-06-2019 at 11:00 am Location : Auditorium Jaques Monod – MONOD (66) ,Institut Pasteur, Paris High-throughput microbiome analysis has become ubiquitous over the last few years. However, the interpretation … Continue reading “New computational tools for the analysis of microbiome dynamics”

Interpreting the cancer genome through physical and functional models of the cancer cell

EVENT : C3BI Seminars Main speaker : Trey Ideker, from UC San Diego – School of Medicine Date : 21-06-2019 at 02:00 pm Location : Jules Bordet room – METCHNIKOFF (67) ,Institut Pasteur, Paris Dr. Ideker is a Professor of Medicine at UC San Diego. He is the Director of the National Resource for Network … Continue reading “Interpreting the cancer genome through physical and functional models of the cancer cell”

Evolution of information in HIV-1 protease

EVENT : C3BI Seminars Main speaker : Chris Adami, from Michigan State University Date : 06-06-2019 at 02:00 pm Location : Auditorium Francois Jacob – BIME (26) ,Institut Pasteur, Paris Highly-active anti-retroviral therapy has been extremely effective at maintaining low levels of viral load in HIV-infected individuals, but emerging drug resistance is threatening those gains. … Continue reading “Evolution of information in HIV-1 protease”

A population genetic interpretation of complex trait architecture in humans

EVENT : C3BI Seminars Main speaker : Guy Sella, from Department of Biological Sciences, Columbia University Date : 02-05-2019 at 02:00 pm Location : Auditorium Francois Jacob – BIME (26) ,Institut Pasteur, Paris Human genome-wide association studies (GWASs) are revealing the genetic architecture of anthropomorphic and biomedical traits, i.e., the frequencies and effect sizes of … Continue reading “A population genetic interpretation of complex trait architecture in humans”