Seminars – Big data in biology : challenges and opportunities

EVENT : C3BI Seminars

Big data in biology : challenges and opportunities


Main speaker : Ewan Birney, from DirectEBI-EMBL Date : 05/10/2017 at 02:00 pm Location : Retrovirus room – LWOFF (22) ,Institut Pasteur, Paris


Ewan Birney:  Co-director of the European Bioinformatic Institute and played a vital role in annotating the genome sequences of human, mouse, chicken and several other organisms. He was one of the founder of the Ensembl Genome Browser and the head of the Encode data analysis group. Ewan is a non-executive Director of Genomics England, and is a consultant and advisor to a number of companies, including Oxford Nanopore Technologies and GSK.
Abstract: Molecular biology is now a leading example of a data intensive science, with both pragmatic and theoretical challenges being raised by data volumes and dimensionality of the data. These changes are present in both “large scale” consortia science and small scale science, and across now a broad range of applications – from human health, through to agriculture and ecosystems. All of molecular life science is feeling this effect. This shift in modality is creating a wealth of new opportunities and has some accompanying challenges. In particular there is a continued need for a robust information infrastructure for molecular biology. This ranges from the physical aspects of dealing with data volume through to the more statistically challenging aspects of interpreting it. A particular problem is finding causal relationships in the high level of correlative data. Drawing on recent experience I will explore both the “blue collar” challenges of data volume and the “white collar” challenges of interpretation. I will end with exploration of linear traits in cardiac biology using large scale cohorts.


Due to security policy in Institut Pasteur, please register before if you plan to come to this meeting